Hazardous substances — data sheets, inventory and thresholds (EU and Italy)
A list of checks and obligations with their cadence, ready to add to your agenda.
European kit for companies that buy, store or use hazardous substances and mixtures, with the Seveso rules applying to Italy. Covers REACH safety data sheets, CLP labelling and storage conditions, the in-house substance inventory, checking quantities against the Seveso thresholds and the resulting duties, and the expiry of PPE and absorbent material. It does NOT cover chemical risk assessment and worker exposure monitoring, carcinogens and asbestos, ADR transport, or the REACH registration duties of manufacturers and importers.
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Ask what is in the manuals, how often the maintenance is due and what it takes to do it.
What it already has at hand
- No manual on this page
- 9 planned checks, the most frequent every 6 months since the last inspection
Planned checks
Informative summary verified on 11/09/2026. It does not replace legal advice: the regulation cited prevails. If you spot an error, report it.
Some checks are only mandatory in certain countries: pick yours and the list follows.
- 01
Check CLP labelling and storage conditions
Check that every container, including decanted ones, carries the full CLP label — pictograms, signal word, hazard statements and precautionary statements — and that storage respects chemical incompatibilities, ventilation and spill containment with bunds, kerbs and impermeable flooring. The evidence is the periodic inspection record with photographs or a signed checklist. Applies to all sites holding hazardous substances or mixtures; spill containment is also required by environmental permits and sewer by-laws to prevent contamination of rainwater.
every 6 months since the last inspectionLegal obligationRegolamento (CE) 1272/2008 artt. 17-33 (CLP); D.Lgs. 81/2008 art. 223European Union onlySourceverified on 11/09/2026 - 02
Check quantities held against the Seveso thresholds
Compare the maximum quantities of hazardous substances present or foreseen on site with the thresholds of Annex 1 to Legislative Decree 105/2015, applying the summation rule for health, physical and environmental hazard categories: crossing a threshold triggers notification duties and, for the upper tier, the safety report. The evidence is the dated and signed applicability calculation. Applies to all establishments holding hazardous substances, including those below the thresholds, because the check is precisely what demonstrates that the rules do not apply, and it must be repeated whenever quantities or products change significantly.
every 12 months since the last inspectionLegal obligationD.Lgs. 26 giugno 2015 n. 105 art. 3 e Allegato 1, nota 4 (regola di sommatoria)Italy onlySourceverified on 11/09/2026 - 03
Review the major-accident prevention policy
The operator reviews the major-accident prevention policy document and the safety management system at least every two years, and in any case whenever changes increase the risk. The evidence is the reviewed document, dated and signed by the operator. Applies to lower-tier and upper-tier establishments.
every 24 months since the last inspectionLegal obligationD.Lgs. 105/2015 art. 14 comma 4 e Allegato BItaly onlySourceverified on 11/09/2026 - 04
Keep the Seveso notification up to date
An in-scope establishment sends the notification with the Annex 5 information to the Ministry, the Region, the Regional Technical Committee, the Prefecture, the Municipality and the Fire Brigade Command and updates it before any change that significantly increases or decreases quantities or alters the nature or physical state of the substances, and before permanent closure: there is no automatic periodic resubmission. The evidence is the notification sent together with the certified e-mail receipts. Applies only to lower-tier and upper-tier establishments under Annex 1.
continuous check, confirm every 12 monthsLegal obligationD.Lgs. 105/2015 art. 13 e Allegato 5Italy onlySourceverified on 11/09/2026 - 05
Check PPE and absorbent material for expiry
Verify that the personal protective equipment for chemical risk — gloves, goggles, masks, filters — is intact, within the manufacturer's expiry date and properly stored, and that spill kits and absorbent material are complete and not degraded, replacing anything expired or used. The evidence is the signed inspection checklist together with the PPE issue register. Applies to all workplaces where hazardous substances or mixtures are handled: mask filters and chemical protective gloves typically have shelf lives of 3 to 5 years from the date of manufacture.
every 6 months since the last inspectionLegal obligationD.Lgs. 81/2008 art. 77 comma 4 lett. a) e comma 5; Regolamento (UE) 2016/425Italy onlySourceverified on 11/09/2026 - 06
Review and test the internal emergency plan
The internal emergency plan is reviewed, tested and, where necessary, updated at appropriate intervals not exceeding three years, taking account of changes in the establishment, in the emergency services and in technical knowledge. The evidence is the emergency drill record together with the updated plan. Applies to lower-tier and upper-tier establishments; the internal emergency plan must not be confused with the external emergency plan, which is the Prefecture's responsibility.
every 36 months since the last inspectionLegal obligationD.Lgs. 105/2015 art. 20 e Allegato 4Italy onlySourceverified on 11/09/2026 - 07
Keep the safety data sheets up to date
Collect from the supplier the safety data sheet of every hazardous substance or mixture, in the national language and in the REACH Annex II format, and periodically verify that you hold the latest revision: the supplier must update the sheet without delay when relevant new information emerges and send it to every recipient supplied in the previous twelve months. The evidence is the archive of sheets with revision date and number. Applies to anyone buying or receiving substances or mixtures classified as hazardous, or unclassified mixtures containing hazardous substances above the threshold concentrations; sheets that do not follow the format of Regulation (EU) 2020/878 are no longer compliant.
continuous check, confirm every 12 monthsLegal obligationRegolamento (CE) 1907/2006 art. 31, in particolare paragrafi 1, 5 e 9; Allegato II come sostituito dal Regolamento (UE) 2020/878European Union onlySourceverified on 11/09/2026 - 08
Review the safety report at least every five years
The operator of an upper-tier establishment reviews the safety report at least every five years, and also after a major accident, on risk-increasing modifications or when new facts justify it, and sends the outcome to the Regional Technical Committee. The evidence is the reviewed safety report together with the transmission receipt. Applies only to upper-tier establishments, that is those in column 3 of Annex 1; lower-tier establishments do not draw up the report but must still document the safety management system.
every 60 months since the last inspectionLegal obligationD.Lgs. 105/2015 art. 15 comma 8, lettera a) e Allegato 2Italy onlySourceverified on 11/09/2026 - 09
Update the hazardous substance inventory
Keep an up-to-date list of all hazardous substances and mixtures present on site, with the maximum quantities held, the storage location, the CLP classification and a reference to the safety data sheet: the inventory underpins the chemical risk assessment and the Seveso threshold check and must be updated whenever a new product is introduced. The evidence is the dated inventory attached to the risk assessment document. Applies to all employers using chemical agents in production or in ancillary maintenance, cleaning and laboratory activities.
continuous check, confirm every 12 monthsLegal obligationD.Lgs. 81/2008 art. 223 comma 1 e art. 28Italy onlySourceverified on 11/09/2026
- 01
Check CLP labelling and storage conditions
Check that every container, including decanted ones, carries the full CLP label — pictograms, signal word, hazard statements and precautionary statements — and that storage respects chemical incompatibilities, ventilation and spill containment with bunds, kerbs and impermeable flooring. The evidence is the periodic inspection record with photographs or a signed checklist. Applies to all sites holding hazardous substances or mixtures; spill containment is also required by environmental permits and sewer by-laws to prevent contamination of rainwater.
every 6 months since the last inspectionLegal obligationRegolamento (CE) 1272/2008 artt. 17-33 (CLP); D.Lgs. 81/2008 art. 223European Union onlySourceverified on 11/09/2026 - 02
Keep the safety data sheets up to date
Collect from the supplier the safety data sheet of every hazardous substance or mixture, in the national language and in the REACH Annex II format, and periodically verify that you hold the latest revision: the supplier must update the sheet without delay when relevant new information emerges and send it to every recipient supplied in the previous twelve months. The evidence is the archive of sheets with revision date and number. Applies to anyone buying or receiving substances or mixtures classified as hazardous, or unclassified mixtures containing hazardous substances above the threshold concentrations; sheets that do not follow the format of Regulation (EU) 2020/878 are no longer compliant.
continuous check, confirm every 12 monthsLegal obligationRegolamento (CE) 1907/2006 art. 31, in particolare paragrafi 1, 5 e 9; Allegato II come sostituito dal Regolamento (UE) 2020/878European Union onlySourceverified on 11/09/2026
- 01
Check CLP labelling and storage conditions
Check that every container, including decanted ones, carries the full CLP label — pictograms, signal word, hazard statements and precautionary statements — and that storage respects chemical incompatibilities, ventilation and spill containment with bunds, kerbs and impermeable flooring. The evidence is the periodic inspection record with photographs or a signed checklist. Applies to all sites holding hazardous substances or mixtures; spill containment is also required by environmental permits and sewer by-laws to prevent contamination of rainwater.
every 6 months since the last inspectionLegal obligationRegolamento (CE) 1272/2008 artt. 17-33 (CLP); D.Lgs. 81/2008 art. 223European Union onlySourceverified on 11/09/2026 - 02
Keep the safety data sheets up to date
Collect from the supplier the safety data sheet of every hazardous substance or mixture, in the national language and in the REACH Annex II format, and periodically verify that you hold the latest revision: the supplier must update the sheet without delay when relevant new information emerges and send it to every recipient supplied in the previous twelve months. The evidence is the archive of sheets with revision date and number. Applies to anyone buying or receiving substances or mixtures classified as hazardous, or unclassified mixtures containing hazardous substances above the threshold concentrations; sheets that do not follow the format of Regulation (EU) 2020/878 are no longer compliant.
continuous check, confirm every 12 monthsLegal obligationRegolamento (CE) 1907/2006 art. 31, in particolare paragrafi 1, 5 e 9; Allegato II come sostituito dal Regolamento (UE) 2020/878European Union onlySourceverified on 11/09/2026
In Switzerland this product has no planned checks: the ones listed apply to other countries.
- 01
Check CLP labelling and storage conditions
Check that every container, including decanted ones, carries the full CLP label — pictograms, signal word, hazard statements and precautionary statements — and that storage respects chemical incompatibilities, ventilation and spill containment with bunds, kerbs and impermeable flooring. The evidence is the periodic inspection record with photographs or a signed checklist. Applies to all sites holding hazardous substances or mixtures; spill containment is also required by environmental permits and sewer by-laws to prevent contamination of rainwater.
every 6 months since the last inspectionLegal obligationRegolamento (CE) 1272/2008 artt. 17-33 (CLP); D.Lgs. 81/2008 art. 223European Union onlySourceverified on 11/09/2026 - 02
Keep the safety data sheets up to date
Collect from the supplier the safety data sheet of every hazardous substance or mixture, in the national language and in the REACH Annex II format, and periodically verify that you hold the latest revision: the supplier must update the sheet without delay when relevant new information emerges and send it to every recipient supplied in the previous twelve months. The evidence is the archive of sheets with revision date and number. Applies to anyone buying or receiving substances or mixtures classified as hazardous, or unclassified mixtures containing hazardous substances above the threshold concentrations; sheets that do not follow the format of Regulation (EU) 2020/878 are no longer compliant.
continuous check, confirm every 12 monthsLegal obligationRegolamento (CE) 1907/2006 art. 31, in particolare paragrafi 1, 5 e 9; Allegato II come sostituito dal Regolamento (UE) 2020/878European Union onlySourceverified on 11/09/2026
In United Kingdom this product has no planned checks: the ones listed apply to other countries.
- 01
Check CLP labelling and storage conditions
Check that every container, including decanted ones, carries the full CLP label — pictograms, signal word, hazard statements and precautionary statements — and that storage respects chemical incompatibilities, ventilation and spill containment with bunds, kerbs and impermeable flooring. The evidence is the periodic inspection record with photographs or a signed checklist. Applies to all sites holding hazardous substances or mixtures; spill containment is also required by environmental permits and sewer by-laws to prevent contamination of rainwater.
every 6 months since the last inspectionLegal obligationRegolamento (CE) 1272/2008 artt. 17-33 (CLP); D.Lgs. 81/2008 art. 223European Union onlySourceverified on 11/09/2026 - 02
Keep the safety data sheets up to date
Collect from the supplier the safety data sheet of every hazardous substance or mixture, in the national language and in the REACH Annex II format, and periodically verify that you hold the latest revision: the supplier must update the sheet without delay when relevant new information emerges and send it to every recipient supplied in the previous twelve months. The evidence is the archive of sheets with revision date and number. Applies to anyone buying or receiving substances or mixtures classified as hazardous, or unclassified mixtures containing hazardous substances above the threshold concentrations; sheets that do not follow the format of Regulation (EU) 2020/878 are no longer compliant.
continuous check, confirm every 12 monthsLegal obligationRegolamento (CE) 1907/2006 art. 31, in particolare paragrafi 1, 5 e 9; Allegato II come sostituito dal Regolamento (UE) 2020/878European Union onlySourceverified on 11/09/2026
- 01
Check CLP labelling and storage conditions
Check that every container, including decanted ones, carries the full CLP label — pictograms, signal word, hazard statements and precautionary statements — and that storage respects chemical incompatibilities, ventilation and spill containment with bunds, kerbs and impermeable flooring. The evidence is the periodic inspection record with photographs or a signed checklist. Applies to all sites holding hazardous substances or mixtures; spill containment is also required by environmental permits and sewer by-laws to prevent contamination of rainwater.
every 6 months since the last inspectionLegal obligationRegolamento (CE) 1272/2008 artt. 17-33 (CLP); D.Lgs. 81/2008 art. 223European Union onlySourceverified on 11/09/2026 - 02
Keep the safety data sheets up to date
Collect from the supplier the safety data sheet of every hazardous substance or mixture, in the national language and in the REACH Annex II format, and periodically verify that you hold the latest revision: the supplier must update the sheet without delay when relevant new information emerges and send it to every recipient supplied in the previous twelve months. The evidence is the archive of sheets with revision date and number. Applies to anyone buying or receiving substances or mixtures classified as hazardous, or unclassified mixtures containing hazardous substances above the threshold concentrations; sheets that do not follow the format of Regulation (EU) 2020/878 are no longer compliant.
continuous check, confirm every 12 monthsLegal obligationRegolamento (CE) 1907/2006 art. 31, in particolare paragrafi 1, 5 e 9; Allegato II come sostituito dal Regolamento (UE) 2020/878European Union onlySourceverified on 11/09/2026
In United States this product has no planned checks: the ones listed apply to other countries.
In Other country this product has no planned checks: the ones listed apply to other countries.
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